COAGULOPATHIES OF LIVER DISEASES: A NARRATIVE REVIEW
Keywords:
Coagulation disorders, Liver diseases, ThrombosisAbstract
Background: Liver is considered to be one of the synthetic organs regarding coagulation factors. Patients with liver
disease undergo a rebalanced state, where a procoagulant state is also established along with an anticoagulant state.
The risk of thrombosis is as common as the risk of bleeding.
Aims and objectives: The following discussion will highlight the importance of rebalanced system and will explain
the role of common coagulation tests in patient with advanced liver disease. This discussion will also emphasize the
limitation of common coagulation tests and will describe an approach to such patients in clinical settings.
Material and Methods: A narrative literature review utilizing PubMed and OVID as databases was carried out in August
2018. Keywords used were: “Advanced liver disease”, “Coagulation disorders”, “Thrombosis and embolism” and
“Coagulopathy of liver diseases”. This literature search was confined only to studies performed on human beings and
published in English language only.
Downloads
Published
How to Cite
Issue
Section
License
All articles published in the Journal of Medical Sciences (JMS) are licensed under the Creative Commons Attribution 4.0 International License (CC-BY 4.0). Under the CC BY 4.0 license, author(s) retain the ownership of the copyright publishing rights without restrictions for their content, and allow others to copy, use, print, share, modify, and distribute the content of the article even for commercial purposes as long as the original authors and the journal are properly cited. No permission is required from the author/s or the publishers for this purpose. Appropriate attribution can be provided by simply citing the original article. The corresponding author has the right to grant on behalf of all authors, a worldwide license to JMS and its licensees in all forms, formats, and media (whether known now or created in the future), The corresponding author must certify and warrant the authorship and proprietorship and should declare that he/she has not granted or assigned any of the article’s rights to any other person or body.
The corresponding author must compensate the journal for any costs, expenses, or damages that the JMS may incur as a result of any breach of these warranties including any intentional or unintentional errors, omissions, copyright issues, or plagiarism. The editorial office must be notified upon submission if an article contains materials like text, pictures, tables, or graphs from other copyrighted sources. The JMS reserves the right to remove any images, figures, tables, or other content, from any article, whether before or after publication, if concerns are raised about copyright, license, or permissions and the authors are unable to provide documentation confirming that appropriate permissions were obtained for publication of the content in question.
