THE TESTOSTERONE STATUS IN OVERWEIGHT YOUNG ADULTS OF PESHAWAR
Article Sidebar
Main Article Content
Abstract
Objective: To see whether obesity decreases the testosterone concentration in young male adults, who have no other
cause of decreased testosterone.
Material & Methods: This was a comparative, case control and cross sectional study conducted in the Department
of Biochemistry, Khyber Medical College, Peshawar - Pakistan. The study period was from January 2016 to December
2016, consisting of two groups, A and B, each having 32 subjects. Group A had BMI of >25 Kg/m2 while the control
group B had BMI of < 25 Kg/m2. Their testosterone concentrations were compared keeping other confounding factors
like age, sex, educational status and socioeconomic conditions constant. The weight in Kg and height in meters were
measured for each subject and then BMI was calculated. A blood sample of approximately 5-ml was collected from
each participant. The sera were prepared and stored in labeled tubes which were then properly sealed, placed in racks
and were stored in a freezer at -20oC till further analysis. The samples were analyzed for serum Testosterone level by
Radioimmunoassay (RIA) method.
Results: Group A had 32 obese subjects having a BMI 26.9 Kg/m2 with a SD of 1.501. The testosterone concentration
of group A is compared with that of control group B having a normal BMI of 21.7 with a SD of 1.557. Testosterone concentrations
of the two study groups revealed a significant difference (P< 0.001) when compared by the independent
sample t-test.
Conclusion: The increase trend of obesity in elderly people and now in young adults should be prevented as it lower
serum testosterone concentrations, apart from other hazards like diabetes, hypertension, CVD and osteoarthritis.
Article Details
All articles published in the Journal of Medical Sciences (JMS) are licensed under the Creative Commons Attribution 4.0 International License (CC-BY 4.0). Under the CC BY 4.0 license, author(s) retain the ownership of the copyright publishing rights without restrictions for their content, and allow others to copy, use, print, share, modify, and distribute the content of the article even for commercial purposes as long as the original authors and the journal are properly cited. No permission is required from the author/s or the publishers for this purpose. Appropriate attribution can be provided by simply citing the original article. The corresponding author has the right to grant on behalf of all authors, a worldwide license to JMS and its licensees in all forms, formats, and media (whether known now or created in the future), The corresponding author must certify and warrant the authorship and proprietorship and should declare that he/she has not granted or assigned any of the article’s rights to any other person or body.
The corresponding author must compensate the journal for any costs, expenses, or damages that the JMS may incur as a result of any breach of these warranties including any intentional or unintentional errors, omissions, copyright issues, or plagiarism. The editorial office must be notified upon submission if an article contains materials like text, pictures, tables, or graphs from other copyrighted sources. The JMS reserves the right to remove any images, figures, tables, or other content, from any article, whether before or after publication, if concerns are raised about copyright, license, or permissions and the authors are unable to provide documentation confirming that appropriate permissions were obtained for publication of the content in question.