PREVALENCE OF HEPATITIS B AND C AND THEIR RISK FACTORS IN PATIENTS ADMITTED IN ORTHOPAEDIC UNIT
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Abstract
Objectives: To find out the prevalence of Hepatitis B and C and there risk factors in patient admitted in Orthopaedic
unit of Khyber Teaching Hospital, Peshawar.
Material and Methods: This single centered descriptive study was carried out in Orthopaedic and Medical units of
Khyber Teaching Hospital, Peshawar, from April 2007 to May 2009. All patients admitted to our unit were enrolled in
the study. They were screened for hepatitis B and C by immunochromatography (ICT) Kit method .Those who were
positive on ICT were confirmed by 3rd generation enzyme linked immunosorbent assay (ELISA) and polymerase
chain reaction (PCR), relevant investigations like liver function tests, abdominal ultrasound, prothrombin time (PT),
activated partial thromboplastin time (APTT) were also done.
Results: Out of 4215 patients, 3202 (75.96%) were male and 1012 (24.04 %) were female. Hepatitis B and Hepatitis C
was present in 392 (9.30%) patients, out of these 392 patients 313 (79.8%) were male and 79 (20.1%) were female.
Hepatitis B was present in 130 (3.08%) patients, hepatitis C was present in 249 (5.90%) patients and 13 (0.09%)
patients were positive for both hepatitis B and hepatitis C. Out of 392 hepatitis positive patients risk factors were
identified among 244 (62.24%) patients, while no risk factor was identified in 148 (37.76 %). History of previous
surgery (20.92%) was the commonest predisposing factors.
Conclusions: High prevalence of hepatitis B and C suggests that pre-operative screening of patients going for
surgery should be mandatory.
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