TREATMENT OF CHRONIC FISSURE-IN-ANO WITH GLYCERYL TRINITRATE
Article Sidebar
Main Article Content
Abstract
Objectives: To determine the role of 0.2% topical glyceryl trinitrate in the treatment for chronic anal fissure.
Material and Methods: This descriptive study was carried out in Khyber Teaching Hospital, Peshawar from January
2004 to September 2007. Patients with a 6 weeks history of primary chronic anal fissure were included in the study. All
patients were diagnosed on the basis of history and clinical examination. After advising application of glyceryl trinitrate
0.2% on the anal verge, patients were followed on 10th, 20th, 40th day and 6 months.
Results: A total of 73, including 58 (79.4%) male and 15 (20.5%) female patients with mean age of 39 years were
included. Complete resolution was observed in 42 (57.5%) patients while 22 (30.1%) cases had partial response, 5
(6.8%) patients had no response. In the failure group 4 patients underwent surgical intervention.
Conclusion: Glyceryl trinitrate (0.2%) cream is an effective treatment for chronic anal fissure, having unnecessary
surgery.
Article Details
All articles published in the Journal of Medical Sciences (JMS) are licensed under the Creative Commons Attribution 4.0 International License (CC-BY 4.0). Under the CC BY 4.0 license, author(s) retain the ownership of the copyright publishing rights without restrictions for their content, and allow others to copy, use, print, share, modify, and distribute the content of the article even for commercial purposes as long as the original authors and the journal are properly cited. No permission is required from the author/s or the publishers for this purpose. Appropriate attribution can be provided by simply citing the original article. The corresponding author has the right to grant on behalf of all authors, a worldwide license to JMS and its licensees in all forms, formats, and media (whether known now or created in the future), The corresponding author must certify and warrant the authorship and proprietorship and should declare that he/she has not granted or assigned any of the article’s rights to any other person or body.
The corresponding author must compensate the journal for any costs, expenses, or damages that the JMS may incur as a result of any breach of these warranties including any intentional or unintentional errors, omissions, copyright issues, or plagiarism. The editorial office must be notified upon submission if an article contains materials like text, pictures, tables, or graphs from other copyrighted sources. The JMS reserves the right to remove any images, figures, tables, or other content, from any article, whether before or after publication, if concerns are raised about copyright, license, or permissions and the authors are unable to provide documentation confirming that appropriate permissions were obtained for publication of the content in question.