VITAMIN B12 DEFICIENCY AMONG PATIENTS WITH MEGALOBLASTIC ANEMIA

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Safia Rehman
Naveed Sharif
Samiyah Rahman
Shams Suleman
Ambreen Gul
Muhammad Abbas

Abstract

Objective: To determine the frequency of vitamin B12 deficiency in different age group of patients with megaloblastic
anemia.
Material & Methods: It is descriptive cross-sectional study in which 84 patients with megaloblastic anemia were selected
at department of pathology Khyber Teaching Hospital Peshawar-Pakistan from January 2018 to June 2018. Patients
were divided in different age of groups. Complete blood count and serum B12 levels were measured.
Results: Among 84 patients, 54 (64.3%) were male while 30 (35.7%) were female. The mean age of participants of
study was 41.9 years (SD ±19.7) with age range from 1 to 85 years. There were 50 (60%) patients with vitamin B12
deficiency. Among patients with vitamin B12 deficiency 32 (64%) were male while 18 (36%) were female. Regarding
various age groups, similar number of patients i.e. 16, reported in each of age group 31 to 45 years and more than 45
years. In age group 16 to 30 years, 14 patients had vitamin B12 deficiency.
Conclusion: Vitamin B12 deficiency is common, irrespective of gender and age groups in megaloblastic anemia patients

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