TREATMENT OF ECLAMPSIA BY MAGNESIUM SULPHATE
Keywords:
Eclampsia, Pritchard regime, Magnesium sulphateAbstract
Objective: To evaluate the effectiveness of low dose magnesium sulphate in control of convulsions in eclampsia and to assess the magnesium related toxicity and pregnancy outcome.
Material and Methods: This prospective study was carried out in the Department of Obstetrics and Gynaecology B Labour Room, Khyber Teaching Hospital, Peshawar from April 2013 to December 2013. Fifty cases of eclampsia were randomly selected for inclusion in the study to find out the efficacy of low dose magnesium sulphate regime to control eclamptic convulsions. Patients were excluded from the study if there were doubts about the diagnosis because the accompanying relatives did not witness the seizure or who has received magnesium sulphate or diazepam as anticonvulsant prior to admission to the hospital. Those patients who presented with complications like cerebrovascular accidents, renal failure, aspiration pneumonitis and Hellp syndrome were also excluded from the study. The loading dose of magnesium sulphate was 9 gm. Following this 2.5 gm was given intramuscularly every four hour for 24 hours. Patients were monitored hourly by observing their respiratory rate, knee jerk and urine output. Maternal and perinatal outcome and magnesium toxicity were analyzed. Standard principles of management of eclampsia was followed.
Results: With low dose magnesium sulphate regime, convulsions were controlled in 100 percent cases. No single case got recurrence or shifting to Pritchard regime.
Conclusion: Low dose magnesium sulphate regime is safe and effective for treatment of eclamptic fits.
Downloads
Published
How to Cite
Issue
Section
License
All articles published in the Journal of Medical Sciences (JMS) are licensed under the Creative Commons Attribution 4.0 International License (CC-BY 4.0). Under the CC BY 4.0 license, author(s) retain the ownership of the copyright publishing rights without restrictions for their content, and allow others to copy, use, print, share, modify, and distribute the content of the article even for commercial purposes as long as the original authors and the journal are properly cited. No permission is required from the author/s or the publishers for this purpose. Appropriate attribution can be provided by simply citing the original article. The corresponding author has the right to grant on behalf of all authors, a worldwide license to JMS and its licensees in all forms, formats, and media (whether known now or created in the future), The corresponding author must certify and warrant the authorship and proprietorship and should declare that he/she has not granted or assigned any of the article’s rights to any other person or body.
The corresponding author must compensate the journal for any costs, expenses, or damages that the JMS may incur as a result of any breach of these warranties including any intentional or unintentional errors, omissions, copyright issues, or plagiarism. The editorial office must be notified upon submission if an article contains materials like text, pictures, tables, or graphs from other copyrighted sources. The JMS reserves the right to remove any images, figures, tables, or other content, from any article, whether before or after publication, if concerns are raised about copyright, license, or permissions and the authors are unable to provide documentation confirming that appropriate permissions were obtained for publication of the content in question.
