HAEMOGLOBANOPATHIES IN SOUTHERN AREAS OF KHYBER PAKHTUNKHWA
Keywords:
Haemoglobanopathies, Thallasemia, sickle cell diseaseAbstract
Objectives: To determine the frequencies of various types of haemoglobanopathies in southern areas of Khyber Pakhtunkhwa.
Material and Methods: This cross sectional study was conducted in Department of Pathology, Gomal Medical College
from January 2014 to October 2014. Relevant information’s notede on a questionnaire prepared in accordance with
the aims and objectives of the study.
Results: A total of 62 patients underwent Hb electrophoresis in Department of Pathology Gomal Medical Collge, Dera
Ismail Khan. 27(43.5%) were females and 35 males (56.5%). Majority of the patients 37(59.7%) were in the age range 3
month to 5 years. We received patients from age 3 month to 60 years age for knowing types of haemoglobanopathies.
The distribution of patients was 49(79%) patients DI Khan, Tank 10(16%), Lakki Marwat 2(3.2%) and South Wazirstan
1(1.6%). The Haemoglobin of all patient as recorded from the peripheral smear. It was observed that 43(55%) patients
had Hb < 8g/dl and were candidates for blood transfusion. Of the above group 17 had Hb ranging from 2.2 to 5g/dl
(severely anemic). The Distribution of various haemoglobanopathies were; Beta thallassemia major 16(25.8%), Beta
Thalassemia trait 7(11.3%), Sickle cell disease 6(9.7%), Sickle cell trait 2(3.2%), Sickle cell/Beta thalassemia (double
heterozygosity) 2(3.2%) and HbE/ Beta Thalassemia (Double heterozygous 1(1.6%). 28(45.2%) had normal Hb Electrophoresis
reports.
Conclusion: Haemoglobanopathies are common in southern areas of Khyber Pakhtunkhwa. Beta thalassemia major
is a major haemoglobanopathy. Sickle cell diseases are also prevalent in this region especially in the Sherani, Baytani
and Ustrana tribes of Dera Ismail Khan.
Downloads
Published
How to Cite
Issue
Section
License
All articles published in the Journal of Medical Sciences (JMS) are licensed under the Creative Commons Attribution 4.0 International License (CC-BY 4.0). Under the CC BY 4.0 license, author(s) retain the ownership of the copyright publishing rights without restrictions for their content, and allow others to copy, use, print, share, modify, and distribute the content of the article even for commercial purposes as long as the original authors and the journal are properly cited. No permission is required from the author/s or the publishers for this purpose. Appropriate attribution can be provided by simply citing the original article. The corresponding author has the right to grant on behalf of all authors, a worldwide license to JMS and its licensees in all forms, formats, and media (whether known now or created in the future), The corresponding author must certify and warrant the authorship and proprietorship and should declare that he/she has not granted or assigned any of the article’s rights to any other person or body.
The corresponding author must compensate the journal for any costs, expenses, or damages that the JMS may incur as a result of any breach of these warranties including any intentional or unintentional errors, omissions, copyright issues, or plagiarism. The editorial office must be notified upon submission if an article contains materials like text, pictures, tables, or graphs from other copyrighted sources. The JMS reserves the right to remove any images, figures, tables, or other content, from any article, whether before or after publication, if concerns are raised about copyright, license, or permissions and the authors are unable to provide documentation confirming that appropriate permissions were obtained for publication of the content in question.
