DIARRHOEA IN PREDOMINANT IRRITABLE BOWEL SYNDROME AND CELIAC DISEASE
Article Sidebar
Main Article Content
Abstract
Objective: To find the frequency of celiac’s disease in patients previously treated for Irritable bowel syndrome by histological
examination of lower duodenal biopsy specimens.
Material and Methods: This was a cross sectional study, including fifty patients, conducted at Department of Medicine,
Khyber Teaching Hospital, Peshawar, Pakistan from February 2013 to May 2013. A total of 50 patients were included in
the study with a mean age of 30 years. Oesophagogastrodeudonoscopy was performed and lower deudonal biopsies
were taken, all specimens were sent in formalin for histopathology examination to screen for villous atrophy.
Results: In this study fifty patients previously treated for Irritable bowel syndrome were evaluated with duodenal biopsy
for celiac's Disease. Twelve patients were found to have biopsy changes consistent with celiac’s disease, resulting in
prevalence of 24%.
Conclusion: Celiac’s disease can cause malabsorption and is a pre-cancerous is condition. A high degree of suspician
is required among physicians for early diagnosis of coeliacs disease and prevention of malignancy.
Article Details
All articles published in the Journal of Medical Sciences (JMS) are licensed under the Creative Commons Attribution 4.0 International License (CC-BY 4.0). Under the CC BY 4.0 license, author(s) retain the ownership of the copyright publishing rights without restrictions for their content, and allow others to copy, use, print, share, modify, and distribute the content of the article even for commercial purposes as long as the original authors and the journal are properly cited. No permission is required from the author/s or the publishers for this purpose. Appropriate attribution can be provided by simply citing the original article. The corresponding author has the right to grant on behalf of all authors, a worldwide license to JMS and its licensees in all forms, formats, and media (whether known now or created in the future), The corresponding author must certify and warrant the authorship and proprietorship and should declare that he/she has not granted or assigned any of the article’s rights to any other person or body.
The corresponding author must compensate the journal for any costs, expenses, or damages that the JMS may incur as a result of any breach of these warranties including any intentional or unintentional errors, omissions, copyright issues, or plagiarism. The editorial office must be notified upon submission if an article contains materials like text, pictures, tables, or graphs from other copyrighted sources. The JMS reserves the right to remove any images, figures, tables, or other content, from any article, whether before or after publication, if concerns are raised about copyright, license, or permissions and the authors are unable to provide documentation confirming that appropriate permissions were obtained for publication of the content in question.