COMPARISON OF DIFFERENT CLINICAL OUTCOMES AMONG ASTHMATIC AND NON-ASTHMATIC COVID-19 PATIENTS IN AN INTENSIVE CARE UNIT SETTING
Article Sidebar
Main Article Content
Abstract
Objectives: To compare the different clinical outcomes among asthmatic and non-asthmatic patients having COVID-19 in an ICU setting
Materials and Methods: A cross-sectional study was conducted in the Covid ICU of Hayatabad Medical Complex Peshawar from April 2021 to September 2022. WHO validated questionnaire was used among 220 study participants who were selected in this study. A modified questionnaire was tested for validation through a pilot study. A Cronbach alpha of less than 0.80 was considered acceptable. A significant P value was considered as < 0.05. SPSS version 22 was used for data analysis.
Results: Out of a total of 220 participants, 10.9% (n= 24) were asthmatic while 89.1% (n= 196) were non-asthmatic. The majority of participants were non-asthmatic male 118 (60.2%, p-value 0.86).
Different comorbidities were seen in different patients, most of the non-asthmatic patients, 81 (41.3%, p-value 0.57) had more than one co-morbidity. Most of the non-asthmatic patients, 178 (90.8%, p-value 0.40) had consolidation on their chest X-rays while 23 asthmatics (95.8%, p-value 0.40) had consolidation on their chest X-rays. The majority of the non-asthmatic patients, 161 (82.1%, p-value 0.23) had high D-dimer levels. Ventilator use in the hospital was found in the majority of the non-asthmatic patients (183/93.4%, p-value 0.75) while, 22 asthmatic patients (91.7%, p-value 0.75) were found to be on a ventilator. The majority of non-asthmatic patients had high levels of serum LDH, D-dimer, and Ferritin. Twenty asthmatic patients (83.3%, p-value 0.21) had severe ARDS, and 169 non-asthmatic patients (86.2%, p-value 0.21) had severe ARDS. The number of days of hospitalization was found more among the majority of the asthmatic patients (23/95.8%, p-value 0.61) and in non-asthmatic patients, 176 (89.8, p-value 0.61) were admitted to the hospital for 20 days.
Conclusion:
COVID-19 disease was found higher among non-asthmatic patients as compared to asthmatic patients. The presence of other significant comorbidities also increases COVID-19 infection severity.
Key Words: Asthmatic, Non-Asthmatic, COVID-19, Comorbidities, Ventilator.
Article Details
This work is licensed under a Creative Commons Attribution 4.0 International License.
All articles published in the Journal of Medical Sciences (JMS) are licensed under the Creative Commons Attribution 4.0 International License (CC-BY 4.0). Under the CC BY 4.0 license, author(s) retain the ownership of the copyright publishing rights without restrictions for their content, and allow others to copy, use, print, share, modify, and distribute the content of the article even for commercial purposes as long as the original authors and the journal are properly cited. No permission is required from the author/s or the publishers for this purpose. Appropriate attribution can be provided by simply citing the original article. The corresponding author has the right to grant on behalf of all authors, a worldwide license to JMS and its licensees in all forms, formats, and media (whether known now or created in the future), The corresponding author must certify and warrant the authorship and proprietorship and should declare that he/she has not granted or assigned any of the article’s rights to any other person or body.
The corresponding author must compensate the journal for any costs, expenses, or damages that the JMS may incur as a result of any breach of these warranties including any intentional or unintentional errors, omissions, copyright issues, or plagiarism. The editorial office must be notified upon submission if an article contains materials like text, pictures, tables, or graphs from other copyrighted sources. The JMS reserves the right to remove any images, figures, tables, or other content, from any article, whether before or after publication, if concerns are raised about copyright, license, or permissions and the authors are unable to provide documentation confirming that appropriate permissions were obtained for publication of the content in question.
