Main Article Content
Objective: To determine the frequency of lactose intolerance in children with severe acute malnutrition presenting with
Material and method: This study was conducted in nutritional rehabilitation unit, Khyber teaching hospital Peshawar
from June 2014 to December 2014. It was a descriptive cross sectional study comprising of 150 paediatric patientsranging
from 5 months to 5 years of age who met the WHO criteria of acute severe malnutrition having Z-score of <-3SD
with weight for height/length, age and sex presenting with diarrhea. Then stool was tested for reducing substances in
freshly collected sample.
Results: Of the total 150 patients of 5-60 months of age (mean age 17.7±11.91 SD), 82(54.7%) were male and 68(45.3%)
were female. Overall 41(27.3%) were lactose intolerant (having diarrhea with positive stool reducing substances)
among them 21 were male (51.2%) while 20 were female (48.7%), 32 patients (78.04%) were having kwashiorkor and
9 patients (21.9%) were marasmic. Perianal rash, abdominal distention were present in 37 (90.2%) and, 38 (92.6 %)
patients respectively. The findings which were significantly observed in children with lactose intolerance were edematous
malnutrition (p-value 0.003), perianal rash (p-value 0.00), and abdominal distention (p-value 0.00).
Conclusion: Secondary lactose intolerance is a common problem of children with acute severe malnutrition presenting
with diarrhea. Clinical signs of lactose intolerance in severely malnourished children are perianalexcoriation of skin
and abdominal distention.
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.
CopyRight . © 2008-2018 Khyber Medical College Peshawar | All Rights Reserved