MATERNAL SERUM VISFATIN LEVEL IN PRE-ECLAMPSIA AND LATE PREGNANCY AND ITS EFFECTS ON BIOCHEMICAL PARAMETERS
Article Sidebar
Main Article Content
Abstract
Objective: To determines and evaluate the quantitative variations in the circulating visfatin in conditions like pre-eclampsia
and to compare with the normal pregnant subjects.
Material and Methods: This study conducted in three tertiary care hospitals (Hayatabad Medical Complex, Lady Reading
Hospital, Khyber Teaching Hospital, Peshawar) from May 2014 to February 2015. It included a total of 160 pregnant women. 86 comprising of PE and while 74 were normal healthy pregnant women with gestational age of more than 20 weeks. Serum visfatin level was determined by enzyme linked immunoassay whereas lipid profile was determined by enzymatic colorimetric methods. Data was analyzed using SPSS version 19.
Results: Among the pre-eclampsia patients seventy five (46.90%) were suffering from severe pre-eclampsia and 6.90% were with mild pre-eclampsia. Serum visfatin was noted to be 4.81±3.11 and 5.48±2.74 ng/mL and were highly significant
(p<0.000) when compared with controls. Similar trends in results were observed for urinary albumin, serum creatinine and blood urea respectively.
Conclusions: Significant difference in the serum visfatin levels of the pre-eclampsia compared to healthy pregnant women was observed.
Article Details
All articles published in the Journal of Medical Sciences (JMS) are licensed under the Creative Commons Attribution 4.0 International License (CC-BY 4.0). Under the CC BY 4.0 license, author(s) retain the ownership of the copyright publishing rights without restrictions for their content, and allow others to copy, use, print, share, modify, and distribute the content of the article even for commercial purposes as long as the original authors and the journal are properly cited. No permission is required from the author/s or the publishers for this purpose. Appropriate attribution can be provided by simply citing the original article. The corresponding author has the right to grant on behalf of all authors, a worldwide license to JMS and its licensees in all forms, formats, and media (whether known now or created in the future), The corresponding author must certify and warrant the authorship and proprietorship and should declare that he/she has not granted or assigned any of the article’s rights to any other person or body.
The corresponding author must compensate the journal for any costs, expenses, or damages that the JMS may incur as a result of any breach of these warranties including any intentional or unintentional errors, omissions, copyright issues, or plagiarism. The editorial office must be notified upon submission if an article contains materials like text, pictures, tables, or graphs from other copyrighted sources. The JMS reserves the right to remove any images, figures, tables, or other content, from any article, whether before or after publication, if concerns are raised about copyright, license, or permissions and the authors are unable to provide documentation confirming that appropriate permissions were obtained for publication of the content in question.