The Diagnostic accuracy of the Belin/Ambrosio enhanced ectasia total deviation display (BAD-D) in diagnosing keratoconus taking tomographic and biomechanical index (TBI) as the gold standard
Keywords:
Corvis biomechanical index, Belin/Ambrosio enhanced ectasia total deviation display; Tomographic and biomechanical indexAbstract
Purpose
To compare the diagnostic ability of the Belin/Ambrosio enhanced ectasia index in keratoconus screening taking tomographic and biomechanical index (TBI) as the gold standard
Methods
One thousand eyes of five hundred patients were included in this cross sectional study. Patients coming to Amanat eye hospital Peshawar from July 2018 to June 2019 for keratorefractive laser procedure or collagen cross linkage were randomly included. Amanat eye hospital Peshawar is a private eye care centre having diagnostic and photorefractive laser treatment facilities. The tools used for the study were the Oculus Pentacam HR and the Corvis ST. SPSS version 23 was used for statistical analysis of collected data.
Results
The mean BAD-D value was 3.080+/- 4.450 SD, the s.e. of the mean was 0.140, 95% confidence interval (c.i.) of 2.805 to 3.356. The range was 0.00 to 40.21.
The mean TBI value was 0.465+/_ 0.392 SD, s.e. was 0.124 with a 95% c. i. of 0.222 to 0.708. The range of TBI was 0.00 to 1.00.
For BAD-D, sensitivity was 75.6%, specificity was 100 %, positive predictive value was 100% and the negative predictive value was 72.3%.
Conclusion
The current study showed acceptable accuracy of BAD-D in terms of specificity and sensitivity. It is recommended that its result should be interpreted along with other topographic, and tomographic parameters.
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