COMPARATIVE LIPID PROFILE AND BLOOD PRESSURE STUDIES IN DIABETIC NON-PROLIFERATIVE AND PROLIFERATIVE RETINOPATHIC MALE PATIENTS
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Abstract
Objectives: To determine the serum lipid profile and blood pressure in male diabetic patients and to compare them
between non-proliferative and proliferative retinopathy.
Material and Methods: A total of 150 male subjects were selected for this prospective and case control study. Four
groups designated as Non Proliferative Diabetic Retinopathic (NPDR, n=48), Proliferative Diabetic Retinopathic (PDR,
n= 68), diabetic Non retinopathic (CDNR, n=16) and normal Subjects (NS, n=18) were formed. Fasting serum total
cholesterol, high density lipoprotein, low density lipoproteins and triglyceride levels were measured in each patient.
Systolic and diastolic blood pressure values were recorded using standard methods. All the data were analysed by
SPSS-16 for comparison between the groups.
Results: Serum low density lipoproteins and triglyceride concentrations were found significantly greater in all the
three diabetic groups being highest in the PDR subjects. High density lipoprotein concentrations were significantly
lower in the CDNR, NPDR & PDR groups as compared to NS group. Total cholesterol did not differ significantly
among the groups. Similarly systolic and diastolic blood pressures were also found to be comparatively higher in the
retinopathic groups.
Conclusion: Higher serum levels of LDL and triglycerides and lower levels of HDL and higher systolic and diastolic
blood pressures are found in type 2 diabetes with retinopathy.
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