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Objective: To evaluate the incidence of thyroid malignancy in multinodular goitre.
Material and Methods: This descriptive study was carried out in the department of ENT and Head and Neck surgery
Khyber Teaching Hospital, Peshawar, form January 2011 to December 2012 All the patients with multi nodular goiter
were evaluated with ultrasound, fine needle aspiration cytology and thyroid function tests, and they were offered surgery
as the treatment for suspicions of malignancy, cosmesis and compression symptom. The specimen were subjected
to histopathological examination to determine the incidence and types of malignancy in multinodular goitre (MNG).
Results: A total of 100 cases were included in this study, among those 75(75%) were females and 25(25%) were male,
Out of 100 patients 85% were benign and 15% were malignant among the malignant tumors, 10(10%) were papillary,
4(4%) were follicular, 1(1%) was medullary carcinoma.
Conclusion: The incidence of malignancy in MNG is quite significant and it is not very low as was thought before
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