ROLE OF ITOPRIDE IN MINIMIZING POST PRANDIAL GLUCOSE EXCURSION IN TYPE 2 DIABETIC PATIENTS
Article Sidebar
Main Article Content
Abstract
Objective: To determine the effect of itopride (Prokinetic) drug on Post Prandial Glycemia in type 2 DM.
Material and Methods: This study was conducted in Department of Medicine and Department of Pharmacology, Khyber Teaching Hospital, Peshawar from January 2012 to December 2012. Total of 100 patients were enrolled in the study and categorized into two treatment groups. Each group contain 50 patients. 1st group (Control group) was given oral anti-diabetic agents and Placebo. 2nd Group (Treatment Group) was given oral anti-diabetic agents along with itopride. Fasting and two hours Post Prandial blood sugar was done. Difference between fasting and 2 hours postmeal glycemic levels were found out and then compared in the two groups.
Results: Mean fasting and post load glucose for Group 1 patient was 155.24 mg/dl and 2 hour post load glucose was 331.80 mg/dl. Group II mean fasting blood sugar was 159.88 mg/dl and mean 2 hours Post Prandial blood sugar was 222.40 mg/dl. Mean difference in fasting and 2 hours post prandial blood sugar was 176.56 mg/dl and 62.52 mg/dlrespectively in Group I and II.
Conclusion: This study showed significant decrease in fasting and post prandial blood sugar level in patient taking itopride as compared to control group.
Article Details
All articles published in the Journal of Medical Sciences (JMS) are licensed under the Creative Commons Attribution 4.0 International License (CC-BY 4.0). Under the CC BY 4.0 license, author(s) retain the ownership of the copyright publishing rights without restrictions for their content, and allow others to copy, use, print, share, modify, and distribute the content of the article even for commercial purposes as long as the original authors and the journal are properly cited. No permission is required from the author/s or the publishers for this purpose. Appropriate attribution can be provided by simply citing the original article. The corresponding author has the right to grant on behalf of all authors, a worldwide license to JMS and its licensees in all forms, formats, and media (whether known now or created in the future), The corresponding author must certify and warrant the authorship and proprietorship and should declare that he/she has not granted or assigned any of the article’s rights to any other person or body.
The corresponding author must compensate the journal for any costs, expenses, or damages that the JMS may incur as a result of any breach of these warranties including any intentional or unintentional errors, omissions, copyright issues, or plagiarism. The editorial office must be notified upon submission if an article contains materials like text, pictures, tables, or graphs from other copyrighted sources. The JMS reserves the right to remove any images, figures, tables, or other content, from any article, whether before or after publication, if concerns are raised about copyright, license, or permissions and the authors are unable to provide documentation confirming that appropriate permissions were obtained for publication of the content in question.