RIGHT ATRIAL MYXOMA ASSOCIATED WITH FATAL THROMBOCYTOPENIA: A RARE CLINICAL ASSOCIATION
Keywords:
atrial myxoma, immune mechanism, mucosal bleeding, paraneoplastic, thrombocytopeniaAbstract
A woman in her sixties with a history of hypertension, type 2 diabetes mellitus, and previously diagnosed right atrial myxoma presented with generalized body swelling, fever, dyspnea, bilateral chest pain, and mucosal bleeding. Laboratory tests showed progressive thrombocytopenia, renal dysfunction, and metabolic acidosis. Despite supportive care, her platelet count decreased from 29 × 10^9/L to 21 × 10^9/L, and she ultimately died from severe thrombocytopenia with mucosal hemorrhage and multi-organ failure. Infectious and hematologic causes were ruled out, and all other common causes were excluded, suggesting a paraneoplastic mechanism related to the right atrial myxoma. This case highlights a rare, potentially fatal hematologic complication of right-sided cardiac myxoma and emphasizes the importance of considering tumor-associated thrombocytopenia in similar situations.
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Copyright (c) 2025 Faisal Iqbal Jadoon, Taimoor Sikandar Zaman Khan, Mujtaba Zahid, Waseem Ahmad Jadoon, Shahzadi Umar
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