CLINICAL EFFECTIVENESS OF AZITHROMYCIN VERSUS CIPROFLOXACIN IN THE TREATMENT OF UNCOMPLICATED ENTERIC FEVER IN CHILDREN;
DOI:
https://doi.org/10.52764/jms.20.28.4.15Keywords:
Azithromycin, Ciprofloxacin, Enteric FeverAbstract
ABSTRACT
Objective: To compare the clinical effectiveness of oral azithromycin with oral ciprofloxacin in the treatment of uncomplicated enteric fever in children.
Material and Methods: A randomized controlled trial was carried out in the Pediatric department of Khyber Teaching Hospital for which a sample size of 282 patients was determined using WHO calculator with 5% level of significance and 80% power of test (Two sided). Non-probability consecutive sampling technique was used for selection of children age 6 to 18 years and either gender. They were divided into two groups (141 in each) where Group A was treated with oral azithromycin while Group B with ciprofloxacin for 7 days. Clinical effectiveness was determined when the patient remained afebrile for more than 48 hours without antipyretics.
Results: In group A, 128 children (90.78%) while in Group B, 105 (74.46%) children become clinically cure.
Conclusion: Oral Azithromycin is more effective than oral Ciprofloxacin in the treatment of typhoid fever in children.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2020 Journal Of Medical Sciences
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
All articles published in the Journal of Medical Sciences (JMS) are licensed under the Creative Commons Attribution 4.0 International License (CC-BY 4.0). Under the CC BY 4.0 license, author(s) retain the ownership of the copyright publishing rights without restrictions for their content, and allow others to copy, use, print, share, modify, and distribute the content of the article even for commercial purposes as long as the original authors and the journal are properly cited. No permission is required from the author/s or the publishers for this purpose. Appropriate attribution can be provided by simply citing the original article. The corresponding author has the right to grant on behalf of all authors, a worldwide license to JMS and its licensees in all forms, formats, and media (whether known now or created in the future), The corresponding author must certify and warrant the authorship and proprietorship and should declare that he/she has not granted or assigned any of the article’s rights to any other person or body.
The corresponding author must compensate the journal for any costs, expenses, or damages that the JMS may incur as a result of any breach of these warranties including any intentional or unintentional errors, omissions, copyright issues, or plagiarism. The editorial office must be notified upon submission if an article contains materials like text, pictures, tables, or graphs from other copyrighted sources. The JMS reserves the right to remove any images, figures, tables, or other content, from any article, whether before or after publication, if concerns are raised about copyright, license, or permissions and the authors are unable to provide documentation confirming that appropriate permissions were obtained for publication of the content in question.
