INFREQUENT ISOLATES ON CULTURE OF CEREBROSPINAL FLUID IN PATIENTS WITH MENINGITIS IN ADULTS

Authors

  • Azmat Ali Department Medicine, KRL Hospital, Islamabad - Pakistan
  • Javaria Ilyas Sheikh Department Medicine, KRL Hospital, Islamabad - Pakistan
  • Ahsan Nisar Department Medicine, KRL Hospital, Islamabad - Pakistan

Keywords:

Meningitis, Antibiotics, Resistance, Staphylococcus aureus, Cryptococcus, Linezolid, Vancomycin

Abstract

Objective: To identify common pathogens causing meningitis, emerging resistance to antibiotics as delay in treatment
may adversely affect outcome.
Material and Methods: It was descriptive observational study which was conducted in the Department of Medicine,
KRL Hospital, Islamabad, Pakistan from January 2014 to December 2016. It enrolled 200 patients with age ranging
from 12 to 90 years in whom meningitis was suspected. Two cerebrospinal fluid (CSF) samples were collected, one
for routine examination while other for culture and sensitivity. Data was analyzed using Statistical package for social
sciences (SPSS) version 20. Frequencies and percentages were taken where required.
Results: Eighteen (9%) patients showed growth of microorganisms. Among culture isolates 17 (8.5%) were bacteria,
1(0.5%) was Cryptococcus. Relatively more cultures were positive in trauma and surgery related patients mainly gram
negative organisms, being sensitive to Tigecycline, Colistin followed by Imipenem/Meropenem. Staphylococcus aureus
was sensitive to Linezolid and Vancomycin. There is increasing resistance to cephalosporin.
Conclusion: Cerebrospinal fluid (CSF) shows low rates of bacterial growth on culture. Emperical therapy may be
tailored according to underlying clinical condition

Downloads

Published

2018-04-14

How to Cite

Ali, A., Sheikh, J. I., & Nisar, A. (2018). INFREQUENT ISOLATES ON CULTURE OF CEREBROSPINAL FLUID IN PATIENTS WITH MENINGITIS IN ADULTS. Journal of Medical Sciences, 26(1), 9–13. Retrieved from https://jmedsci.com/Jmedsci/article/view/481

Issue

Vol. 26 No. 1 (2018): Contents

Section

Articles

License

All articles published in the Journal of Medical Sciences (JMS) are licensed under the Creative Commons Attribution 4.0 International License (CC-BY 4.0).  Under the CC BY 4.0 license, author(s) retain the ownership of the copyright publishing rights without restrictions for their content, and allow others to copy, use, print, share, modify, and distribute the content of the article even for commercial purposes as long as the original authors and the journal are properly cited.  No permission is required from the author/s or the publishers for this purpose.  Appropriate attribution can be provided by simply citing the original article. The corresponding author has the right to grant on behalf of all authors, a worldwide license to JMS and its licensees in all forms, formats, and media (whether known now or created in the future), The corresponding author must certify and warrant the authorship and proprietorship and should declare that he/she has not granted or assigned any of the article’s rights to any other person or body.

The corresponding author must compensate the journal for any costs, expenses, or damages that the JMS may incur as a result of any breach of these warranties including any intentional or unintentional errors, omissions, copyright issues, or plagiarism. The editorial office must be notified upon submission if an article contains materials like text, pictures, tables, or graphs from other copyrighted sources. The JMS reserves the right to remove any images, figures, tables, or other content, from any article, whether before or after publication, if concerns are raised about copyright, license, or permissions and the authors are unable to provide documentation confirming that appropriate permissions were obtained for publication of the content in question.