MISOPROSTOL IS SAFE FOR LABOUR INDUCTION IN TERM PREGNANCIES
Keywords:
Prostaglandins, misoprostol, induction, intra uterine death, caesarean sectionAbstract
Objectives: To know about the success of labour induction with the use of 50ug oral misoprostol for induction of
labour at term.
Material and Methods: This is an observational study, which has been conducted in Gynae A unit of Mardan medical
complex hospital Mardan. One hunderd women with full term gestation including primigravidas and multigravidas ,who
required induction had been included in this study. Fifty micro gram misoprostol has been given by oral rout. The dose
was repeated 4hourly and maximum 4 doses had been used.
Results: Doses which had been required by these patients are given in the results. 40% of patients required single
dose of oral 50 ug misoprostol, however 60% had required more than 2 doses for start of labour.Labour started within
12 hours in 55% of patients after start of induction. Seventyfive percent had normal vaginal delivery, while 25% had
caesarean section. The indications for ceasarean section were meconium staining of liquor and abnormal CTG in 16
patients, failure to progress in 6 patients, chorioamnionitis in 2 and failed induction in 1 patient. Maternal adverse effects
were very minimal. The neonatal out come was also better and no neonatal death had occured.
Conclusion: Low doses misoprostol is very much effective for inductions of labour at term.
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