EFFECT ON FETAL BIRTH WEIGHT OF EARLY VERSUS LATE ONSET ECLAMPSIA
Keywords:
Eclampsia, fetus, birth weightAbstract
Objective: To compare the effect on fetal birth weight of early onset versus late onset eclampsia.
Material and Methods: This descriptive study was conducted in the Gynae C unit of Department of Obstetrics and
Gynecology, Khyber Teaching Hospital, Peshawar from January 2009 to December 2009. Patients who presented
with eclampsia were included in the study. A detailed history was taken and examination done and a proforma was
filled. Forty-one live singleton infants were born after eclamptic pregnancies. We compared the weight of those with
a sample of 41 infants born during the same period to normotensive patients with a similar period of gestation.
Result: Among primigravida early onset eclampsia was associated with significant reduction in fetal weight. However
babies of those who developed late onset eclampsia were of comparable weight to the babies of non-eclamptics. In
cases of multiparas, eclampsia of both early and late onset was associated with significant reduction in fetal weight.
Conclusion: Pre-eclampsia is an etiologically heterogeneous disorder that occurs in at least two subsets, one with
normal or enhanced placental function and the other involving placental dysfunction. It is unlikely that a single
treatment or preventive measure will be effective. In further studies it may be important to study the two subtypes
separately.
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