DISSEMINATED INTRAVASCULAR COAGULATION. A CAUSE OF MATERNAL MORTALITY IN PERI-PARTUM PATIENTS
Keywords:
Disseminated, Intravascular, Coagulation, peripartum, maternal, mortalityAbstract
Objective: To find out maternal risk factors causing Disseminated Intravascular Coagulation (DIC) and prevention of
mortality.
Material and methods: This cross sectional study was carried out on a sample population of 23 patients out of total
patients numbering 5726. Sampling method was convenient sampling i.e. patients visiting Khyber Teaching Hospital
during peri partum period. A questionnaire was designed with questions regarding Post-Partum Haemorrhage (PPH),
amniotic Fluid Embolims, Abruptio placentae, Eclampsia, Septic Abortion, Burns, History of Surgery, Heat Stroke,
transfusion reaction and snake bites. The study was carried out from January 2012 to January 2013. Multidisciplinary
approach was carried out according to international protocols. Diagnosis of DIC was based on a clinical
assessment as well as global DIC screening. Specific treatment was carried out which included fluid therapy, Fresh
Frozen Plasma (FFP), red cells concentrate and platelets concentrate in addition to correction of underlying obstetric
disorder.
Results: A total of 23 sample population was treated. Out of these 15(65.2%) patients recovered and 8(34.7%) died
giving a death rate of 34.7%. This study helped us to develop standard operating procedures for reduction in
maternal mortality rate.
Conclusion: Prompt termination of pregnancy, together with supportive measures of necessary to reduce the
complications of Disseminated Intravascular Coagulation
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