COMPARATIVE STUDY OF CONVENTIONAL AND NATURAL TREATMENTS FOR FIRST- AND SECOND-DEGREE UTERINE PROLAPSE: A QUASI-EXPERIMENTAL COMPARATIVE STUDY
DOI:
https://doi.org/10.52764/jms.26.34.3.4Keywords:
Uterine prolapse, nutraceutical therapy, conventional treatment, pelvic floor dysfunction, randomized controlled trialAbstract
Objective: This quasi-experimental study aimed to explore a multi-pathway herbal matrix as a viable alternative to standard mechanical treatment.
Methods: A prospective observational cohort study was conducted with 125 patients at Khyber Teaching Hospital in Peshawar. Rather than randomization, patients were assigned to two groups based on individual circumstances. Participants were encouraged to choose based on their preferences and symptoms. One group received standard pessaries and pelvic floor muscle training. The other group received a standardized botanical preparation suspended in an Evening Primrose Oil bilipid matrix, designed to minimize hepatic first-pass metabolism. Treatment progress was assessed using POP-Q and PFDI-20 scores over a 12-week period.
Results: Both regimens showed substantial baseline improvements. However, the oral botanical treatment arm had a more pronounced reduction in structural POP-Q staging (p = 0.035) and in subjective PFDI-20 symptom burden (p = 0.029). The non-invasive cohort reported superior tolerability, with no severe adverse events and a comparatively low 9.5% incidence of mild gastrointestinal shifts, versus 19.3% localized irritation in the mechanical treatment arm. Overall satisfaction was 83.1% in the botanical treatment arm.
Conclusion: Our findings suggest that nutraceutical therapy is a viable, noninvasive alternative for managing mild uterine prolapse, offering outcomes comparable to or better than those of traditional methods and with better patient tolerability.
Keywords: Uterine Prolapse, Phytoestrogens, Nutraceuticals, Pelvic Floor
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Copyright (c) 2026 Sadia Nasir, Nasreen Kishwar, Ziad Ullah Shah, Habib Ullah Mohsin, Hamdi Iqbal Bangesh
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