TY - JOUR AU - Dodhy, Afia Arshed PY - 2020/12/31 Y2 - 2024/03/29 TI - COMPARISON OF DEXMEDETOMIDINE AND ONDANSETRON FOR PREVENTION OF SHIVERING IN LOWER LIMB SURGERIES AFTER SPINAL ANAESTHESIA JF - Journal of Medical Sciences JA - JMS VL - 28 IS - 4 SE - Articles DO - 10.52764/jms.20.28.4.11 UR - https://jmedsci.com/index.php/Jmedsci/article/view/984 SP - 356-360 AB - <p><strong>Objective:</strong> The purpose of the study was to compare the effectiveness of dexmedetomidine and ondansetron to prevent shivering in patients&nbsp; undergoing lower limb surgeries after spinal anaesthesia .</p><p><strong>Methods: </strong>This &nbsp;randomised&nbsp; double-blind and&nbsp; placebo-control study trial was held in orthopaedic operation theatre of Lahore General Hospital, Lahore from February 2020 to June 2020. Total of 120&nbsp; adult patients &nbsp;who underwent elective orthopaedic surgery of lower limbs after spinal anaesthesia &nbsp;were divided&nbsp; into 3 batches. In Batch S, saline was given as&nbsp; placebo, in Batch O ondansetron and in Batch D dexmedetomidine was administered and shivering score were assessed for 45 min. A shivering score of&nbsp;&nbsp; ? 3 was considered as primary outcome.</p><p><strong>Results: </strong>There is &nbsp;statistically considerable difference, in the incidence of significant shivering (grade 3 &amp; 4), among batches, as established by one way ANOVA. The significance value is 0.004 (i.e. p=0.004). There was no significant difference statistically between batch D and batch O (p=0.878)</p><p><strong>Conclusion:</strong> The incidence of shivering in batch S&nbsp; was considerably higher than&nbsp; that of both Batch O and&nbsp; batch D while no significant relationship could be proved in between batch D and batch O</p><p><strong>Key words: </strong>Dexmedetomedine, Ondansetron, Shivering, Spinal Anaesthesia</p> ER -