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Objective: The purpose of the study was to compare the effectiveness of dexmedetomidine and ondansetron to prevent shivering in patients undergoing lower limb surgeries after spinal anaesthesia .
Methods: This randomised double-blind and placebo-control study trial was held in orthopaedic operation theatre of Lahore General Hospital, Lahore from February 2020 to June 2020. Total of 120 adult patients who underwent elective orthopaedic surgery of lower limbs after spinal anaesthesia were divided into 3 batches. In Batch S, saline was given as placebo, in Batch O ondansetron and in Batch D dexmedetomidine was administered and shivering score were assessed for 45 min. A shivering score of ≥ 3 was considered as primary outcome.
Results: There is statistically considerable difference, in the incidence of significant shivering (grade 3 & 4), among batches, as established by one way ANOVA. The significance value is 0.004 (i.e. p=0.004). There was no significant difference statistically between batch D and batch O (p=0.878)
Conclusion: The incidence of shivering in batch S was considerably higher than that of both Batch O and batch D while no significant relationship could be proved in between batch D and batch O
Key words: Dexmedetomedine, Ondansetron, Shivering, Spinal Anaesthesia
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