COMPARISON OF DEXMEDETOMIDINE AND ONDANSETRON FOR PREVENTION OF SHIVERING IN LOWER LIMB SURGERIES AFTER SPINAL ANAESTHESIA

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Afia Arshed Dodhy

Abstract

Objective: The purpose of the study was to compare the effectiveness of dexmedetomidine and ondansetron to prevent shivering in patients  undergoing lower limb surgeries after spinal anaesthesia .


Methods: This  randomised  double-blind and  placebo-control study trial was held in orthopaedic operation theatre of Lahore General Hospital, Lahore from February 2020 to June 2020. Total of 120  adult patients  who underwent elective orthopaedic surgery of lower limbs after spinal anaesthesia  were divided  into 3 batches. In Batch S, saline was given as  placebo, in Batch O ondansetron and in Batch D dexmedetomidine was administered and shivering score were assessed for 45 min. A shivering score of   ? 3 was considered as primary outcome.


Results: There is  statistically considerable difference, in the incidence of significant shivering (grade 3 & 4), among batches, as established by one way ANOVA. The significance value is 0.004 (i.e. p=0.004). There was no significant difference statistically between batch D and batch O (p=0.878)


Conclusion: The incidence of shivering in batch S  was considerably higher than  that of both Batch O and  batch D while no significant relationship could be proved in between batch D and batch O


Key words: Dexmedetomedine, Ondansetron, Shivering, Spinal Anaesthesia

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How to Cite
Dodhy, A. A. (2020). COMPARISON OF DEXMEDETOMIDINE AND ONDANSETRON FOR PREVENTION OF SHIVERING IN LOWER LIMB SURGERIES AFTER SPINAL ANAESTHESIA. Journal of Medical Sciences, 28(4), 356–360. https://doi.org/10.52764/jms.20.28.4.11
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