CLINICAL AND HEMATOLOGICAL FEATURES OF LEISHMANIASIS IN A TERTIARY CARE HOSPITAL OF PESHAWAR
Article Sidebar
Main Article Content
Abstract
Objective: To evaluate the hematological and clinical features of Visceral and Cutaneous Leishmaniasis.
Materials and Methods: This was hospital-based retrospective study which included all cases of Cutaneous leishmaniasis and Visceral leishmaniasis that were diagnosed from Jan 2018 till December 2019 at Pathology Department, Rehman Medical Institute, Peshawar. The diagnosed cases were analyzed for clinical and laboratory profile in details, results of CBC, demographic information and physical signs at presentation were noted as well as bone marrow aspirations were performed for LD bodies.
Results: Out of 104 cases, 36 (34.61%) visceral leishmaniasis and 68 (65.38%) cutaneous leishmaniasis were observed during the study period, in which 82 (78.85%) were male and 22 (21.15%) were females. Age range was from 03-40 years with mean of 23 + 4.21 years. Intermittent fever was observed in almost all the cases of visceral leishmaniasis and 52 (76.47%) of cutaneous leishmaniasis. All patients with visceral leishmaniasis had hepatomegaly and splenomegaly. Patients with CL presented as lesions on face and foot region. In VL all patients were male, while in CL 46 were males and only 22 were females. Majority (83.33%) of patients in VL were children (age group 1-10 years), in cutaneous leishmaniasis 34 (50%) were in age group 31-40 years.
Conclusion: Our study concludes that leishmaniasis mainly affecting age group 10-20 years. Patients with visceral Leishmaniasis presented with pallor, weight loss fever and splenomegaly while those with cutaneous leishmaniasis presented with lesions on the foot and face especially nose. Anemia and thrombocytopenia were most common hematological parameters. It is essential that the Public Health authorities be more aware of the condition in order to improve environmental sanitation and personal protective measures and to establish diagnostic laboratories for early and correct diagnosis and treatment.
Article Details
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
All articles published in the Journal of Medical Sciences (JMS) are licensed under the Creative Commons Attribution 4.0 International License (CC-BY 4.0). Under the CC BY 4.0 license, author(s) retain the ownership of the copyright publishing rights without restrictions for their content, and allow others to copy, use, print, share, modify, and distribute the content of the article even for commercial purposes as long as the original authors and the journal are properly cited. No permission is required from the author/s or the publishers for this purpose. Appropriate attribution can be provided by simply citing the original article. The corresponding author has the right to grant on behalf of all authors, a worldwide license to JMS and its licensees in all forms, formats, and media (whether known now or created in the future), The corresponding author must certify and warrant the authorship and proprietorship and should declare that he/she has not granted or assigned any of the article’s rights to any other person or body.
The corresponding author must compensate the journal for any costs, expenses, or damages that the JMS may incur as a result of any breach of these warranties including any intentional or unintentional errors, omissions, copyright issues, or plagiarism. The editorial office must be notified upon submission if an article contains materials like text, pictures, tables, or graphs from other copyrighted sources. The JMS reserves the right to remove any images, figures, tables, or other content, from any article, whether before or after publication, if concerns are raised about copyright, license, or permissions and the authors are unable to provide documentation confirming that appropriate permissions were obtained for publication of the content in question.
