THE RELATIONSHIP OF CONSANGUINITY WITH CONGENITAL HEART DISEASE IN CHILDREN
Article Sidebar
Main Article Content
Abstract
Objectives: To find the relationship between consanguineous marriage and congenital heart disease in children.
Material and Methods: This case-control study was conducted from October 2018 to January 2020 at inpatient and outpatient settings of department of child health, Khyber teaching hospital Peshawar. Total 346 children were taken and divided into two equal groups. 173 with congenital heart disease and 173 with no cardiac defect on echocardiography. Consecutive non-probability sampling was employed and echocardiographs of the children were collected and analyzed by SPSS 23.
Results: Out of 346 children from birth to 15 years old, 173 had congenital heart disease and 173 had no cardiac defect. 214(61.8%) were male while 132(38.2%) were female. 274(71.1%) were from 0-1 year age group, 66(19.1%) were from 1-5 years, 20(5.8%) from 5-10 years age group and only 14(4%) were from 10-15 years age group. From the total study population, 119(34.39%) had consanguineous parents and had congenital heart disease with the odds of congenital heart disease 1.68 higher in consanguineous marriages compared to non-consanguineous marriages.
Conclusion: The odds of having congenital heart disease is 1.68 higher in children born from consanguineous marriages compared to non-consanguineous marriages.
Article Details
All articles published in the Journal of Medical Sciences (JMS) are licensed under the Creative Commons Attribution 4.0 International License (CC-BY 4.0). Under the CC BY 4.0 license, author(s) retain the ownership of the copyright publishing rights without restrictions for their content, and allow others to copy, use, print, share, modify, and distribute the content of the article even for commercial purposes as long as the original authors and the journal are properly cited. No permission is required from the author/s or the publishers for this purpose. Appropriate attribution can be provided by simply citing the original article. The corresponding author has the right to grant on behalf of all authors, a worldwide license to JMS and its licensees in all forms, formats, and media (whether known now or created in the future), The corresponding author must certify and warrant the authorship and proprietorship and should declare that he/she has not granted or assigned any of the article’s rights to any other person or body.
The corresponding author must compensate the journal for any costs, expenses, or damages that the JMS may incur as a result of any breach of these warranties including any intentional or unintentional errors, omissions, copyright issues, or plagiarism. The editorial office must be notified upon submission if an article contains materials like text, pictures, tables, or graphs from other copyrighted sources. The JMS reserves the right to remove any images, figures, tables, or other content, from any article, whether before or after publication, if concerns are raised about copyright, license, or permissions and the authors are unable to provide documentation confirming that appropriate permissions were obtained for publication of the content in question.