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Objectives: This randomized controlled trial was performed to examine the effectiveness of HPmax regime, a traditional medicine preparation, among 85 duodenal ulcer patients with H. pylori (+).
Methods: The intervention group (n = 42) used HPmax regimen and the control group (n = 43) used Omeprazole, Amoxicillin and Clarithromycine (OAC) regimen.
Results: The number of patients having type A pain relief in intervention group (33.3%) was higher than that in control group (23.3%) (p> 0.05). There were 59.5% patients in the intervention group not having H.pylori after treatment, which was lower than that of control group (69.8%) (p> 0.05). The rate of complete healing in the HPmax group reached 68.2%, equivalent to the rate of complete healing in the patients using OAC (71.1%) (p> 0.05). There are no serious adverse effects between the two groups.
Conclusions: These findings depicted the potential of HPmax in clinical settings in order to reduce the burden of duodenal ulcers with H.pylori infection.
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