PHARMACOLOGICAL SCREENING OF HYPERICUM OBLONGIFOLIUM FOR ITS ANALGESIC EFFECT IN MICE.
Main Article Content
Abstract
Objective
The present study investigates the anti-nociceptive activity of crude methanol extract of Hypericum oblongifolium.
Methods
In vivo acetic acid induced writhing test was used for anti-nociceptive effects at 10mg, 20 mg and 30 mg/kg body wt. respectively intraperitoneally.
Results:
The extract doses of 10, 20 and 30 mg/kg i.p. revealed significant inhibitory effect (P < 0.001) in acetic acid induced writhing test.
Conclusions:
The methanol extract of medicinal plant Hypericum oblongifolium showed significant analgesic / anti-nociceptive effects in animal models and thus validates the traditional uses of the plant in painful conditions.
Key Words
Hypericum oblongifolium, Methanol extract, Anti-nociceptive activity,
Article Details
Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.
CopyRight . © 2008-2021 Khyber Medical College Peshawar | All Rights Reserved.