PHARMACOLOGICAL SCREENING OF HYPERICUM OBLONGIFOLIUM FOR ITS ANALGESIC EFFECT IN MICE.

Main Article Content

Jamshed Ali
Faryal Ali
Arsalan Khan
Muhammad Junaid

Abstract

Objective


 The present study investigates the anti-nociceptive activity of crude methanol extract of Hypericum oblongifolium.


Methods


In vivo acetic acid induced writhing test was used for anti-nociceptive effects at 10mg, 20 mg and 30 mg/kg body wt. respectively intraperitoneally.


Results:


The extract doses of 10, 20 and 30 mg/kg i.p. revealed significant inhibitory effect (P < 0.001) in acetic acid induced writhing test.


Conclusions:


The methanol extract of medicinal plant Hypericum oblongifolium showed significant analgesic /  anti-nociceptive effects in animal models and thus validates the traditional uses of the plant in painful conditions.


 


Key Words


Hypericum oblongifolium, Methanol extract, Anti-nociceptive activity,

Article Details

How to Cite
AliJ., AliF., KhanA., & JunaidM. (2020). PHARMACOLOGICAL SCREENING OF HYPERICUM OBLONGIFOLIUM FOR ITS ANALGESIC EFFECT IN MICE. Journal Of Medical Sciences, 28(3), 260-264. Retrieved from https://jmedsci.com/index.php/Jmedsci/article/view/794
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