ETIOLOGY OF LIVER CIRRHOSIS IN DISTRICT BUNER, KHYBER PAKHTUNKHWA

Abstract

Objective:

The aim of our study was to determine the most common cause of liver cirrhosis in district Buner.

Methodology:

This was retrospective cross-sectional study. Data was collected from patient’s record register from January 2016 till December 2018. A total of 203 patients were included in this study. Data was collected and entered and analyzed in IBM SPSS 23.

Results:

Out of 203 cases, 135(66.5%) were males and 68 (33.5%) were females. The main cause of cirrhosis was HCV (n=163, 80.3%) and HBV (n=27, 13.3%). Cryptogenic cirrhosis occurred in 9 cases (4.4%) while others were only 1% (n=2). HCV was more positive in males (n=108, 66.25%) than in females (n=55, 33.7%), this was statistically significant with a p value .022.

Conclusion:

We conclude with our study that HCV is major cause of Liver Cirrhosis in our patients. HCV is more common in males than in females. Cirrhosis occurs most commonly in 4^th, 5^th and 6^th decades of life after being infected with HBV and HCV.

Keywords: Liver cirrhosis, Hepatitis C virus, Hepatitis B virus, Pakistan.