ETIOLOGICAL SPECTRUM OF PANCYTOPENIA IN PAEDIATRIC PATIENTS
Main Article Content
Abstract
Objective: To determine the etiological pattern of pancytopenia in pediatric age group patients presenting to a tertiary
care hospital at Peshawar
Material and Methods: This descriptive study was conducted from January 2016 to December 2017. During this twoyear
duration, 100 pediatric patients with clinical diagnosis of pancytopenia were enrolled in the study fulfilling the
inclusion and exclusion criteria. Non-probability consecutive sampling technique was used. A detailed clinical evaluation
was done in all diagnosed cases of pancytopenia. Hematological profile included hemoglobin, red cell indices, total
and differential leukocyte counts, platelet count, peripheral blood smear, bone marrow aspirate and trephine biopsy
were carried out.
Results: In this study 66% were male and 34% were female with male to female ratio of 1.94: 1. The mean age of patients
enrolled was 07.173 years+3.7702 SD where 35% of all cases were in the age range of 01-05 years.Mean hemoglobin
level was 6.631gm%+ 2.0273 mean total leucocyte count was 2910.21 (SD + 1399.452)X 103/?l, and platelet count
was 57750.00 (SD + 40776.646) X103/?l. Majority of the patients (51%) had acute lymphoblastic leukemia, followed
by aplastic aneamia(20%) and hypoplasia (12%).
Conclusion: Acute lymphoblastic leukemia is the commonest cause of pancytopenia followed by aplastic aneamia
and bone marrow hypoplasia as per this study findings.
Article Details
All articles published in the Journal of Medical Sciences (JMS) are licensed under the Creative Commons Attribution 4.0 International License (CC-BY 4.0). Under the CC BY 4.0 license, author(s) retain the ownership of the copyright publishing rights without restrictions for their content, and allow others to copy, use, print, share, modify, and distribute the content of the article even for commercial purposes as long as the original authors and the journal are properly cited. No permission is required from the author/s or the publishers for this purpose. Appropriate attribution can be provided by simply citing the original article. The corresponding author has the right to grant on behalf of all authors, a worldwide license to JMS and its licensees in all forms, formats, and media (whether known now or created in the future), The corresponding author must certify and warrant the authorship and proprietorship and should declare that he/she has not granted or assigned any of the article’s rights to any other person or body.
The corresponding author must compensate the journal for any costs, expenses, or damages that the JMS may incur as a result of any breach of these warranties including any intentional or unintentional errors, omissions, copyright issues, or plagiarism. The editorial office must be notified upon submission if an article contains materials like text, pictures, tables, or graphs from other copyrighted sources. The JMS reserves the right to remove any images, figures, tables, or other content, from any article, whether before or after publication, if concerns are raised about copyright, license, or permissions and the authors are unable to provide documentation confirming that appropriate permissions were obtained for publication of the content in question.