CLINICAL PRESENTATION OF NEWLY DIAGNOSED ACUTE LEUKAEMIA PATIENTS IN A TERTIARY CARE HOSPITAL
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Abstract
Objective: To determine the frequency of clinical presentation of newly diagnosed 50 patients of acute leukaemia.
Material & Methods: This study was conducted at Department of Paediatrics, Khyber Teaching Hospital, Peshawar,
Pakistan from March 2016 to September 2017. A cross-sectional descriptive study design was used and 50 patients
presenting with fever, pallor, organomegaly and diagnostic evidence of newly diagnosed acute leukaemia were elected
through non randomised convenient sampling. Common clinical features were noted along with hematological parameters.
The cases were then managed according to standardized management criteria.
Results: Pallor (80%) fever high grade (78%) splenomegaly (62%) were the most common clinical features. Bone
marrow examination showed total 46 (92%) patients of ALL and 4 (8%) patients of AML.
Conclusion: In our study we found out that acute lymphoblastic leukaemia was the most common type of leukaemia
comprising of 46 (92%) patients and 4 (8%) patients were acute myelogenous leukaemia. Fever and Pallor are the
commonest clinical findings of acute leukaemia. Bone marrow examination is mandatory for the diagnosis because
delay in the diagnosis will adversely affect the management.
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