CLINICAL PROFILE OF ULCERATIVE COLITIS

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Ijaz Mohammad Khan
Mohammad Javed
Muhammad Kamran Hassan
Shabir Ahmad Khan
Sher Rehman

Abstract

Objectives: To study the clinical profile of ulcerative colitis (UC) in patients admitted to a tertiary care hospital in Peshawar.
Material and Methods: The study was conducted in the Department of Gastroenterology and Hepatology,
Postgraduate Medical Institute Hayatabad Medical Complex, Peshawar, from January 2007 to December 2008. A
total of hundred patients of previously established as well as newly diagnosed cases of ulcerative colitis were
included in the study. A detailed history was taken and a thorough physical examination was performed on every
patient. All patients were investigated with flexible sigmoidoscopy/ Colonoscopy and findings were recorded on a
standard proforma. The results were analyzed using SPSS version 10.
Results: Out of 100 patients studied, 64 (64%) were male and 36 (36%) were female. The majority (56%) of patients
were between 10 -30 years of age.The age range was 5 -70 years. The mean age was 26.08 years. Eighty percent of
the patients were from Northern areas and 16% from Southern areas of NWFP. Ninety percent of patients presented
with intestinal symptoms like bloody diarrhoea and abdominal pain. Clinically 56% of the patients had severe
disease, 24% moderate disease and 20% had mild disease. On colonoscopy 12% of the patients had proctosigmoiditis,
56% left sided colitis and 32% had pancolitis. Twenty six percent of patients presented with extra intestinal
manifestations.
Conclusion: Ulcerative colitis is more common in young males, most of them present with severe disease and extra
intestinal manifestations are not very rare.

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