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Objectives: To identify the common bacterial pathogens responsible for UTI along with their antimicrobial susceptibility.
Material and Methods: The study was conducted in the Department of Pathology, Khyber Medical College, Peshawar
and Mardan Medical Complex, Mardan. A total of 95 patients with history of UTI (58 Females & 37 males) were included
in the study. Urinary Samples were collected and cultured. Antibiotic sensitivity against the cultured organisms were
tested with “amikacin, nitrofurantoin, co-trimoxazole, imipenam, cefipime, cephalothin, cefotaxime, cefalexin, ceftazidime,
levofloxacin, tobramycin, norfloxacin, cefuroxime and Nalidixic acid”. Culture showed Escherichia Coli ( E.Coli ) at
76.8% followed by Pseudomonas aeroginosa(6.3%), Citrobacter fruendii(3.15%), Enterobacter spp (2.1%), Morganella
sp (2.1%), Staphylococcus aureus (1.05%) and Proteus mirabilis(1.05%). E. coli sensitivity to antibiotics varied from
93% for Imipenemto 02% for NalidixicAcid. Ampicillin was reported as the most resistant antibiotic for E. coli (100%).
Pseudomonas spp. was susceptible to Imipenem (100%) and 100% resistant to many antibiotics.
Conclusion: E.coli and Pseudomonas aeroginosa are responsible for urinary tract infection. E. coli is most susceptible
to ciprofloxacin, which should be the first line of treatment in UTI.
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