COMPARISON OF EFFICACY OF AMOXICILLIN CLAVULANATE AND LEVOFLOXACIN IN TREATMENT OF ACUTE BACTERIAL SINUSITIS
Article Sidebar
Main Article Content
Abstract
Objective: To compare the efficacy of Amoxicillin-Clavulanate and Levofloxacin in the treatment of acute bacterial
rhinosinusitis in terms of complete resolution of signs and symptoms.
Material and Methods: This was a Randomized control study conducted at the ENT Department of Ayub Medical
Institute (AMI), Abbottabad and Khyber Teaching Hospital (KTH), Peshawar from January 2014 to June 2014. A total of
360 patients included in this study were divided in to two groups by non probability technique. Group A included 180
patients who received Amoxicillin-Clavulanate while Group B received levofloxacin for 10 days. Patients were reevaluated
for complete resolution of signs and symptoms on 11th day.
Results: A total of 360 patients were included with a mean age of 31.16 ± 12.51 years. On the 11th day a total of 317
(88.1%) patients had complete resolution of symptoms and signs including 161 (89.44%) of group A and 156 (86.66%)
of group B. There was no statistically significant difference in the frequency of patients and duration of resolution of
signs and symptoms between the two groups.
Conclusion: There was no significant difference in the frequency of patients who had complete resolution of signs
and symptoms between the Amoxicillin-Clavulanate and Levofloxacin receiving patients; hence the two drugs were
similar in efficacy.
Article Details
All articles published in the Journal of Medical Sciences (JMS) are licensed under the Creative Commons Attribution 4.0 International License (CC-BY 4.0). Under the CC BY 4.0 license, author(s) retain the ownership of the copyright publishing rights without restrictions for their content, and allow others to copy, use, print, share, modify, and distribute the content of the article even for commercial purposes as long as the original authors and the journal are properly cited. No permission is required from the author/s or the publishers for this purpose. Appropriate attribution can be provided by simply citing the original article. The corresponding author has the right to grant on behalf of all authors, a worldwide license to JMS and its licensees in all forms, formats, and media (whether known now or created in the future), The corresponding author must certify and warrant the authorship and proprietorship and should declare that he/she has not granted or assigned any of the article’s rights to any other person or body.
The corresponding author must compensate the journal for any costs, expenses, or damages that the JMS may incur as a result of any breach of these warranties including any intentional or unintentional errors, omissions, copyright issues, or plagiarism. The editorial office must be notified upon submission if an article contains materials like text, pictures, tables, or graphs from other copyrighted sources. The JMS reserves the right to remove any images, figures, tables, or other content, from any article, whether before or after publication, if concerns are raised about copyright, license, or permissions and the authors are unable to provide documentation confirming that appropriate permissions were obtained for publication of the content in question.