DIAGNOSTIC ACCURACY OF DIFFUSION WEIGHED MAGNETIC RESONANCE IMAGING IN THE DIAGNOSIS OF MYOMETRIAL INVASION AMONG PATIENTS WITH ENDOMETRIAL CARCINOMA

Authors

  • Humaira Anjum a:1:{s:5:"en_US";s:22:"Khyber Medical College";}
  • Muska Khattak
  • Mahnoor Rehman Hayatabad Medical Complex
  • Samia Iftikhar

DOI:

https://doi.org/10.52764/jms.24.32.1.7

Abstract

OBJECTIVE: To determine diagnostic accuracy of diffusion weighed magnetic resonance imaging in the diagnosis of myometrial invasion in patients with endometrial carcinoma keeping histopathology as gold standard.

MATERIALS AND METHODS:  This was a descriptive cross-sectional study conducted from 11-July-2019 to 10-July-2021 at Radiology Department, Khyber Teaching Hospital, Peshawar. Sample was collected via Non probability sampling technique. Sample size was 141 taking the prevalence of myometrial invasion 46% 12 with sensitivity and specificity of DW-MRI 90% and 73% ,95% confidence level and 10% margin of error. All women presenting with biopsy proven endometrial carcinoma scheduled for hysterectomy, in age between 30 to 70 years were included. Myometrial invasion via MRI pelvis including DWI, with 1.5 T machine (Philips), was evaluated for all patients. After hysterectomy, myometrial invasion was confirmed on histopathology.

RESULTS: Among 141 women, 58 (41%) patients were in 30-50 years age group and 83(59%) patients were in 51-70 years age group. DW-MRI had 91.11% sensitivity, 66.66% specificity, 98.4% Positive predictive value, 25% Negative predictive value and 90.07% diagnostic accuracy

CONCLUSION: DW-MRI has good diagnostic accuracy in the detection of myometrial invasion in endometrial carcinoma.

Key words: Diffusion weighted magnetic resonance imaging, Endometrial cancer, Histopathology.

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Published

2025-11-12

How to Cite

Anjum, H., Khattak, M., Rehman, M. ., & Iftikhar, S. (2025). DIAGNOSTIC ACCURACY OF DIFFUSION WEIGHED MAGNETIC RESONANCE IMAGING IN THE DIAGNOSIS OF MYOMETRIAL INVASION AMONG PATIENTS WITH ENDOMETRIAL CARCINOMA. Journal of Medical Sciences, 32(1). https://doi.org/10.52764/jms.24.32.1.7