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OBJECTIVE: To determine the relationship of Hs-CRP with type 2 diabetes mellitus in patients with acute myocardial infarction.
MATERIALS AND METHODS: It was a cross-sectional study conducted at Hayatabad Medical Complex, Rehman Medical Institute, and Khyber Girls Medical College Peshawar. A total of 90 subjects were enrolled in the study. These subjects were split into two equal groups; Group 1 comprised patients having type 2 diabetes mellitus (T2DM) and acute myocardial infarction (acute MI). Group 2 comprised patients having T2DM only. Patients from both genders who presented within 6-12 hours of acute MI were selected for group 1.
RESULTS: Mean age of subjects of group 1 was greater than that of group 2 while the number of males within group 1 was greater than that of females. The median values of Hs-CRP were higher in group 1 subjects as compared to group 2. There was a significant difference between the values of both groups.
CONCLUSION: The Hs-CRP values were higher in diabetic patients with acute MI as compared to those with diabetes alone because the patients who suffered from acute MI had enhanced ongoing low-grade inflammatory process which was a possible reason for their MI.
KEYWORDS: type 2 diabetes mellitus, coronary artery disease, hs-CRP, myocardial infarction, atherosclerosis.
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