MICROBIOLOGICAL PROFILE AND COMMONLY USED ANTIBIOTICS SUSCEPTIBILITY PATTERN OF ISOLATES AMONG BURN PATIENTS AT A TERTIARY CARE HOSPITAL
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Abstract
Objective: To assess frequency of different pathogens in burn patients and susceptibility pattern of commonly used antibiotics.
Material and Methods: In this prospective study, burn patients (admitted or visited OPD) of Ayub Teaching Hospital, Abbottabad, Pakistan from January 2013 to December 2015 were registered. Mainly wound swab and blood specimen (along with all sort of culturing isolates) were collected from burn patients and were cultured by aseptic conventional method with the intention of observing microbial pathogens. Microbiological profile and antibiotic susceptibility pattern was collected using standard collection techniques and analyzed at local private laboratory.
Results: Among total 491 clinical isolates, 241 (49%) were observed positive. Frequency of pathogens isolated; Pseudomonas
aeruginosa 163 (68%), Staphylococcus aureus 43(18%), E.coli 14(6%), Candida albicans 10(4%), Klebsiella pneumoniae 6 (2%), Salmonella species 2(1%), Proteus species 2(1%) and 1(0.4%) Streptococcus pyogenes. Among these isolates Pseudomonas aeruginosa, Escherichia coli and Staphylococcus Aureus revealed 80±10 % resistant to Ampicillin, Co-Amoxiclav, Amoxicillin, Clarithromycin, Methicillin, and Vancomycin. The rate of bacteremia was 49% among burn patients isolates.
Conclusion: Regular antibiotic sensitivity testing should be done for each patient in order to select an appropriate antimicrobial agent.
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