ASSOCIATION BETWEEN VITAMIN D DEFICIENCY AND DEPRESSIVE ILLNESS IN ADULT POPULATION

Jan-i-Alam1, Sahibzada Saeed Jan2

1Department of Physiology, Pak International Medical College, Hayatabad, Peshawar - Pakistan
2Department of Physiology, Saidu Medical College, Swat - Pakistan

Abstract

Objectives: To study association of vitamin D deficiency and depressive illness in adults.
Material and Methods: The study was conducted in a Private hospital in Hayatabad from May 2015 to December
2015. A total of 340 patients with depression were enrolled in study. Age range was 15 to 70 years. It consisted of
equal number of male and female patients i.e. 170 each. Samples of bloods (4ml) were collected from these patients
by vanupuncture by disposable syringe after overnight fasting and stored at -18oC. The variables which were studied
are age, gender, serum levels of vitamin D, serum Ca levels and history of depression. SPSS-version-10 for windows
was used to analyse the study. P value of <0.05 was considered significant statistically.
Results: 76% i.e. 258 were vitamin D deficient (cut off value 30 ng/ml). This number comprised 186(72%) females and
72(28%) males. Low serum calcium was observed among 25.5% patients with low vitamin D and depression. Among
females 36.8% observed veil (Pardah) and in this group 82% had low serum vitamin D levels. Most of the female patients
were from low socio-economic group.
Conclusion: Vitamin D deficiency is common in adult patients with depression.

Keywords: Vitamin D deficiency, Risk factors, depression.

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